Any maternal exposure to fluconazole during pregnancy — whether in low or high doses — may increase the risk for spontaneous abortion, and high-dose fluconazole during the first trimester may increase the risk for cardiac septal closure anomalies, researchers reported recently in the Canadian Medical Association …
Is it safe to take fluconazole while pregnant?
Although treatment with oral fluconazole during pregnancy is generally discouraged,1 approximately 4% of pregnant women in the United States use fluconazole.
Can fluconazole cause a miscarriage?
Specifically, women who took a lower dose of fluconazole (under 150 milligrams) had more than a doubling of their odds for miscarriage, compared to women who hadn’t taken the drug while pregnant. The increase in risk more than tripled for women who had taken fluconazole at a higher dose, Berard’s team found.
Can fluconazole cause miscarriage in early pregnancy?
“Any maternal exposure to fluconazole during pregnancy may increase risk of spontaneous abortion and doses higher than 150 mg during the first trimester may increase risk of cardiac septal closure anomalies,” study authors conclude, adding that their results are consistent with other research.
Can fluconazole cause birth defects?
Oral fluconazole treatment has been linked to a distinct pattern of birth defects in five infants of mothers who were treated for severe fungal infections with 400 to 800 mg daily during most or all of the first trimester of pregnancy.
What happens if I take fluconazole without a yeast infection?
If you don’t really have a yeast infection, antifungals won’t help you get better. They can actually prolong the real problem, because while you’ll think you’re treating the issue, the real cause will continue to develop.
Can you take a yeast infection pill while pregnant?
Oral medication isn’t recommended if you’re pregnant. Some commonly prescribed antifungals — such as fluconazole (Diflucan) — should be avoided, especially during the first trimester.
How can I treat a yeast infection while pregnant?
Treating a Yeast Infection During Pregnancy
It’s safe to treat a yeast infection with over-the-counter (OTC) vaginal creams or suppositories that contain miconazole or clotrimazole. Don’t take an oral fluconazole tablet to treat a yeast infection during pregnancy. It may cause birth defects.
Which antifungal drug is safe in pregnancy?
Imidazoles are considered safe as topical therapy for fungal skin infections during pregnancy. Nystatin is minimally absorbed and is effective for vaginal therapy.
How long does fluconazole stay in your system?
This medication works in the body for several days after you take the dose. To avoid the risks of harm to the developing baby, if you could become pregnant, be sure to use an effective form of birth control for 7 days after taking this medication.